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6. Fine particulate matter and out-of-hospital cardiac arrest of ...
Particulate matter is a potential risk factor for out-of-hospital cardiac arrests (OHCAs) of respiratory origin. The percent increase in incidence of OHCA ...
Exposure to ambient air pollution increases mortality and is a leading contributor to the global disease burden [1]. Epidemiological studies have elucidated a relationship between out-of-hospital cardiac arrests (OHCAs) and air pollutants, especially particulate matter (diameter ≤2.5 μm; PM2.5) [2, 3]. The causes of OHCA are broadly categorised as cardiac and non-cardiac [4]. A 10 µg·m−3 increase in PM2.5 exposure yielded a 1.6% increase in the incidence of cardiac origin OHCA [3, 5]. However, few studies on OHCAs of non-cardiac origin, including intrinsic respiratory diseases (COPD/pneumonia/asthma) are available. We examined the association between short-term exposure to PM2.5 and bystander-witnessed respiratory origin OHCAs, including eventual prognosis. We also investigated differences between PM2.5 exposure-related cardiac and respiratory origin OHCAs. Particulate matter is a potential risk factor for out-of-hospital cardiac arrests (OHCAs) of respiratory origin. The percent increase in incidence of OHCA of respiratory origin is equivalent to that of PM2.5 exposure-related OHCAs of cardiac origin.
7. Fine particulate matter and out-of-hospital cardiac arrest of ...
Fine particulate matter and out-of-hospital cardiac arrest of respiratory origin ; Sunao Kojima ; Takehiro Michikawa ; Kunihiko Matsui ; Hisao Ogawa ; Shin Yamazaki ...
Particulate matter (diameter ≤2.5 μm; PM2.5) is a potential risk factor for out-of-hospital cardiac arrests (OHCAs) of respiratory origin. The percent increase in incidence of OHCA of respiratory origin is equivalent to that of PM2.5 exposure-related OHCAs of cardiac origin. Footnotes This manuscript has recently been accepted for publication in the European Respiratory Journal . It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article. Conflict of Interest: Dr. Kojima reports grants and personal fees from Teijin Pharma, Ltd., grants from Daiichi Sankyo Company, Ltd., grants from Chugai Pharmaceutical Company, Ltd., grants from Bayer Yakuhin, Ltd., outside the submitted work. Conflict of Interest: Dr. Michikawa has nothing to disclose. Conflict of Interest: Dr. Matsui has nothing to disclose. Conflict of Interest: Dr. Ogawa reports personal fees from Bayer Yakuhin, personal fees from Novartis Pharma, personal fees from Bristol-Meyers Squibb, personal fees from Pfizer, personal fees from Towa Pharmaceutical, outside the submitted work. Conflict of Interest: Dr. Yonemoto has nothing to disclose. Conflict of Interest: Dr. Nitta has nothing to disclose. Conflict of Interest: Dr. Takami reports grants and personal fee...
8. Erj Inmates Mugshots - Printable
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11. Markers of sudden cardiac arrest in patients with severe respiratory ...
The sudden cardiac arrest (SCA) in patients hospitalized due to severe ... ERJ Open Research · European Respiratory Review · Breathe · ERS books online · ERS ...
Introduction . The sudden cardiac arrest (SCA) in patients hospitalized due to severe respiratory infection is a stubborn problem. Often it occurs suddenly and outside the intensive care unit (ICU) [Dr. Carr et al. In-Hospital Cardiac Arrest Among Patients With Coexisting Pneumonia: A Report From The American Heart Association, Abstract of American Thoracic Society's 2011 International Conference in Denver]. However predictors of SCA are still unclear. Aims and objectives. The aim of the study was the analysis of SCA frequency in severe respiratory infection and studying of factors associated with it. Methods. 55 pts with severe respiratory infections in ICU and respiratory department were examined. Respiratory infections (severe pneumonias) were verified on the basis of existence of lung infiltrate according on a chest X-ray or CT-scans. All of the patients recieved additional oxygen or respiratory support, antibiotics and fluid resuscitation. Multifactorial regression analysis and the relative risk indicator were calculated. Results. Despite a carried-out intensive care 22 pts (40%) died. The sudden cardiac arrest occurred in 8 pts (36,3%), not because of septic shock or multiorgan dysfunction. All of patients at the time of SCA were in full consciousness, and the probable cause of SCA was the cardiac arrhythmia. The multiple regression analysis showed that the main predictors of SCA were the extended QT interval (RR=2,2 [1,3; 3;8]) and the low level of SpO2 (<90%) (RR=3,4...
12. From arrest to «party» in the UAE: Where 6 business jets of ...
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13. Inmate Lookup - Berkeley County Sheriff's Office
Date Range of Arrest: Please Note: Partial searches are allowed. If you do not know the ...
Current inmate population:Males: 384Females: 53
14. Erj Mugshots
Erj Mugshots · Active Inmate by Sentencing County or Institution - OIS Search · Arre.st - ERJ, WestVirginia arrest records · Arre.st - ERJ, West Virginia arrest ...
The following is public information. The WV Regional Jails updates this information regularly. This information can change quickly. Therefore, the information may not reflect the true current location, release date, status, or other information regarding an offender. While the information is believed to be accurate, the WV Regional Jails makes ...
15. Post-intubation cardiac arrest events in patients of acute respiratory failure
Does the incidence of post-intubation cardiac arrest differ between depolarizing and nondepolarizing NMBs? ... ERJ Open Research · European Respiratory Review ...
Objective: For RSI, Nondepolarizing NMB has gradually replaced succinylcholine. However, its long-duration paralysis effect may prolong the vulnerable status of critically ill patients after intubation. Does the incidence of post-intubation cardiac arrest differ between depolarizing and nondepolarizing NMBs? Methods: A retrospective analysis of acute respiratory failure patients who received RSI in a university hospital in the past 12 years. Results: ![Figure][1] Demographic data: ![Figure][1] Outcomes: View this table: Conclusion: After RSI, the mortality at ED and the incidence of CPR events within 6 hours during hospitalized patients are similar between different choices of NMBs. The combined data show that succinylcholine is associated with higher cardiac arrest events. Footnotes Cite this article as: European Respiratory Journal 2023; 62: Suppl. 67, PA3565. This abstract was presented at the 2023 ERS International Congress, in session “Inflammatory endotyping: the macrophage across disease areas”. This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at [www.ers-education.org][2] (ERS member access only). [1]: pending:yes [2]: http://www.ers-education.org
16. Modification of azithromycin to counter its arrest of autophagy
Abstract · Jump To · Navigate · About the ERJ · The European Respiratory Society · ERS publications · Help · For authors.
Aim: We have shown that Azithromycin (AZM) blocks airway epithelial cell autophagy. This is contrary to autophagy and AZM’s role of clearing intracellular microbes, and hence may promote bacterial residence and tolerance. Hypothesis: Altering the charge state of AZM or cotreatment with promoters of autophagy counters AZM’s off-target block of autophagy. Method: The 16HBE14o- line was used to model/assess autophagy. Synthetic chemistry was used to produce an oxidised form of AZM, termed Δ-AZM. In parallel experiments, the autophagy promoters Ku-0063794 (KU) or Torin-1 were co-treated with conventional AZM. Structure-activity analyses were then performed by quantifying the abundance of LC3-II (indispensable for autophagy) vs Sequestosome (decreases when autophagy is promoted), to generate a readout for autophagic-flux using Western blot analysis. Results: KU (10 uM) or Torin-1 (5-10 nM) significantly released AZM-based (50 ug/mL) block of autophagy ( P<0.01 ). 9a-NBD-AZM (a fluorescent AZM analogue) loaded into 16HBE14o- cells exposed to KU, showed this was achieved by the cells synthesising further autophagosomes. Δ-AZM significantly mitigated blockade of autophagic flux vs conventional AZM ( P<0.001 ). However, Δ-AZM exhibited a lower bacteriostatic effect in an E coli model and reduced anti-inflammatory properties, as determined using LPS stimulation and readouts for IL-6. Conclusion: We provide proof of concept that AZM-mediated autophagic blockade can be mitigated with...
17. Impact of limbs pneumatic compression during ...
Impact of limbs pneumatic compression during cardiopulmonary resuscitation (CPR) on the survival of cardiac arrest patients ... ERJ Open Research · European ...
Background: Limbs pneumatic compression during cardiopulmonary resuscitation for cardiac arrest patient were rarely reported. We aimed to evaluate the impact of this therapy on the patients with cardiac arrest. Methods: A prospective and controlled study, a total of 46 elderly(74.8±5.3 yrs) cardiac arrest patients were included and randomized to “CPR group “(n=23) and “CPR + Pneumatic Compression group” (n=23). Each in CPR group accepted standard CPR. In addition to standard CPR, all subjects in “Pneumatic Compression group” received intermittent pneumatic compression(IPC) by Air Compression Therapy System, which digital six-tiered rippling full-body pressure (0.45～0.6kg/cm2) and 1 minute interval every 3 minutes. Results: Patients with standard CPR had higher incidence of acute kidney injury than in “CPR + Pneumatic Compression group” (52.2% vs. 21.7%, p =0.032). The lower occurrence of hypoxic ischemic encephalopathy and significant improvements of survival were recorded in Pneumatic Compression group than in CPR group(Figure 1,Figure 2). Conclusions: Intermittent limbs pneumatic compression during cardiopulmonary resuscitation maybe improve survival of cardiac arrest and considered as an optimizing strategy for CPR. ![Figure][1] Footnotes Cite this article as Eur Respir J 2022; 60: Suppl. 66, 23. This article was presented at the 2022 ERS International Congress, in session “-”. This is an ERS International Congress abstract. No full-text version is availa...
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